SHAPING THE FUTURE WITH THE SWIRLING FLOW STENT
n (Life Sciences & Allied Applications / Biology) the mimicking of life using imitation biological systems
In his paper in Nature 19691, Professor Caro proposed that regions of low wall shear in the human arterial system are predisposed to the development of atheroma. This highly significant discovery subsequently contributed to the understanding that post-interventional neointimal hyperplasia also preferentially affects low wall shear regions caused by flow disturbance.
A fundamental characteristic of the body’s arterial system is non-planar geometry and the 3D vascular curvature inherent in non-planarity is an important factor influencing arterial flows, including the elevation of protective wall shear.
1 Caro CG, Fitz-Gerald JM, Schroter RC. Arterial wall shear and distribution of early atheroma in man. Nature. 1969;223:1159 –1160.